PRECLINICAL DEVELOPMENT OF A FIRST-IN-CLASS VACCINE ENCODING HER2, BRACHYURY AND CD40L FOR ANTIBODY ENHANCED TUMOR ERADICATION

Preclinical development of a first-in-class vaccine encoding HER2, Brachyury and CD40L for antibody enhanced tumor eradication

Abstract The induction of antiviral innate immunity by systemic immunization with BLACK SALT FINE live virus can be employed to positively impact the response to therapeutic vaccination.We previously demonstrated that systemic immunization with a non-replicating MVA encoding CD40 ligand (CD40L) enhances innate immune cell activation and function, a

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ATP11B inhibits breast cancer metastasis in a mouse model by suppressing externalization of nonapoptotic phosphatidylserine

Cancer metastasis is the cause of the majority of cancer-related deaths.In this study, we demonstrated that no expression or low expression of ATP11B in conjunction with high expression of PTDSS2, which was negatively regulated by BRCA1, markedly accelerates tumor metastasis.Further analysis revealed that cells with low Jandy AquaLink Parts ATP11B

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Service access experiences of immigrant and refugee caregivers of autistic children in Canada: A scoping review.

Primary caregivers are the main mediators of care for children with an autism diagnosis in Canada, and the navigation process to gain access to autism-related services is known to be a major burden.These challenges to service access are Desk Lamp compounded for newcomers to Canada, which include immigrants and refugees.The purpose of this scoping r

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Development of a novel self-sanitizing mask prototype to combat the spread of infectious disease and reduce unnecessary waste

Abstract With the spread of COVID-19, significant emphasis has been placed on mitigation techniques such as mask wearing to slow infectious disease transmission.Widespread use of face coverings has revealed challenges such as mask contamination and waste, presenting an opportunity to improve the current technologies.In response, we FAT DIGESTIVE EN

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